Human VCAM-1 / CD106 Protein, Fc Tag, premium grade, Unconjugated
Artikelnummer:
ABS-VC1-H5253-1MG
Hersteller Artikelnummer:
VC1-H5253-1mg
Alternativnummer:
ABS-VC1-H5253-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Iglike C2type (immunoglobulinlike) domains. CD106 / VCAM1 is expressed on inflammed vascular endothelium, as well as on macrophagelike and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM1 is Important in cellcell recognition and appears to function in leukocyteendothelial cell adhesion. CD106 / VCAM1 interacts with the beta1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM100 / VCAM1 binds to ECMVD capsid proteins and acts as a receptor for this virus. - Proteine/Peptide
