Human Vitronectin / VTN Protein, Tag Free, low endotoxin, Unconjugated
Artikelnummer:
ABS-VIN-H5214-1MG
Hersteller Artikelnummer:
VIN-H5214-1mg
Alternativnummer:
ABS-VIN-H5214-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Vitronectin is also known as Sprotein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a celltosubstrate adhesion molecule. Inhibitor of the membranedamaging effect of the terminal cytolytic complement pathway. - Proteine/Peptide