Functional NS5B (HCV) Antibody, mAb (blocking), Clone: [5B-12B7], Monoclonal

Artikelnummer: ABT-ADP0014-U0100
Artikelname: Functional NS5B (HCV) Antibody, mAb (blocking), Clone: [5B-12B7], Monoclonal
Artikelnummer: ABT-ADP0014-U0100
Hersteller Artikelnummer: ADP0014-U0100
Alternativnummer: ABT-ADP0014-U0100-100UG
Hersteller: Abcepta
Kategorie: Antikörper
Applikation: ICC, IP
Alternative Synonym: Nonstructural Protein 5B
The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
Klonalität: Monoclonal
Konzentration: 1mg/ml
Klon-Bezeichnung: [5B-12B7]
Antibody Type: Monoclonal Antibody