Ornithine Decarboxylase-1 (ODC-1) Antibody - With BSA and Azide, Clone: [ODC1/486], Mouse, Monoclonal
Artikelnummer:
ABT-AH12026-U0100
Hersteller Artikelnummer:
AH12026-U0100
Alternativnummer:
ABT-AH12026-U0100-100UG
Hersteller:
Abcepta
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FC, IF, IHC, WB
Spezies Reaktivität:
Human, Rat
Alternative Synonym:
Ornithine decarboxylase, ODC, 4.1.1.17, ODC1
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
