NR3C1 Antibody, Clone: [740CT12.1.5], Mouse, Monoclonal

Produktübersicht

• Artikelname: NR3C1 Antibody, Clone: [740CT12.1.5], Mouse, Monoclonal
• Artikelnummer: ABT-AM2187B-EV
• Hersteller Artikelnummer: AM2187b-ev
• Alternativnummer: ABT-AM2187B-EV-80UL
• Hersteller: Abcepta
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse
• Alternative Synonym: Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL

Produktbeschreibung

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [740CT12.1.5]
• Molekulargewicht: 85659
• NCBI: 2908
• UniProt: P04150
• Formulierung: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
• Target-Kategorie: This NR3C1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from human NR3C1.