GABA Transporter (GAT) 2 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: GABA Transporter (GAT) 2 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AN1129
• Hersteller Artikelnummer: AN1129
• Alternativnummer: ABT-AN1129-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Rat
• Alternative Synonym: Sodium- and chloride-dependent GABA transporter 2, GAT-2, Solute carrier family 6 member 13, Slc6a13, Gabt2, Gat-2

Produktbeschreibung

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 68263
• NCBI: 171163
• UniProt: P31646
• Formulierung: Prepared from rabbit serum by affinity purification.
• Target-Kategorie: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
• Antibody Type: Polyclonal Antibody