Anti-Interferon-alpha Receptor, Type I, Subunit I (Ser535,539) Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Anti-Interferon-alpha Receptor, Type I, Subunit I (Ser535,539) Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AN1429
• Hersteller Artikelnummer: AN1429
• Alternativnummer: ABT-AN1429-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Alternative Synonym: Alpha-Type Antiviral Protein, AVP, Beta-Type Antiviral Protein, CRF2-1, Cytokine Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, IFN-Alpha/Beta Receptor 1, IFNBR, IFN-Alpha-REC, IFNAR, IFN-R-1, IFRC, Interferon Alpha/Beta Receptor 1, Interferon-Alpha/Beta Receptor Alpha Chain, Interferon Alpha And Beta Receptor Subunit 1, Interferon (Alpha, Beta And Omega) Receptor 1, Interferon-Beta Receptor 1, Interferon Receptor 1, Type I Interferon Receptor 1

Produktbeschreibung

Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron, 2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-alpha Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine-535 and Ser-539 in the IFNAR1 (Kumar et al., 2003).

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 63525
• NCBI: 3454
• UniProt: P17181
• Formulierung: Antigen Affinity Purified from Pooled Serum
• Target-Kategorie: Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron, 2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Int