Anti-Semaphorin-3A (Central region) Antibody, IgG1, Clone: [M317], Mouse, Monoclonal

Produktübersicht

• Artikelname: Anti-Semaphorin-3A (Central region) Antibody, IgG1, Clone: [M317], Mouse, Monoclonal
• Artikelnummer: ABT-AN1942
• Hersteller Artikelnummer: AN1942
• Alternativnummer: ABT-AN1942-100UL
• Hersteller: Abcepta
• Wirt: Mouse
• Kategorie: Antikörper
• Alternative Synonym: Sema3A, Semaphorin III

Produktbeschreibung

One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A-containing region. Thus, Sema3A and its co-receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [M317]
• Molekulargewicht: 88889
• Isotyp: IgG1
• NCBI: 10371
• UniProt: Q14563