Anti-IKK gamma (C-terminal) Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Anti-IKK gamma (C-terminal) Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AN2064
• Hersteller Artikelnummer: AN2064
• Alternativnummer: ABT-AN2064-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Alternative Synonym: IKBKG, IkB kinase associated protein 1, NEMO, IkB kinase subunit gamma, AMCBX1, FIP3, Ikbkg, IKKAP1, IKKg, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, NF kappa B essential modifier, IP

Produktbeschreibung

Pro-inflammatory cytokines activate the transcription factor NF-kappaB by stimulating the activity of a protein kinase that phosphorylates IkappaB, an inhibitor of NF-kappaB, at sites that trigger its ubiquitination and degradation. A large, cytokine-responsive IkappaB kinase (IKK) complex contains 2 subunits, IKK-alpha and IKK-beta, which are protein kinases whose function is needed for NF-kappaB activation by pro-inflammatory stimuli. IKK is composed of similar amounts of IKK-alpha, IKK-beta, which are differentially processed forms of a third subunit, IKK-gamma. IKK-gamma interacts preferentially with IKK-beta and is required for the activation of the IKK complex.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 48198
• NCBI: 8517
• UniProt: Q9Y6K9