Anti-Musashi 1 Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AN2162
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| Artikelname: | Anti-Musashi 1 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AN2162 |
| Hersteller Artikelnummer: | AN2162 |
| Alternativnummer: | ABT-AN2162-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Alternative Synonym: | MSI1, RNA-binding protein Musashi homolog 1 |
| Musashi 1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi 1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinsons. The presence of Msi-1 in a significant percentage of neurons containing cytoplasmic inclusions in 2 other neurodegenerative diseases Alzheimers disease and Pick disease suggests that it may play a role in the pathogenesis of these neurodegenerative disorders. Musashi 1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection. |
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