Anti-Noggin Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AN2168
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| Artikelname: | Anti-Noggin Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AN2168 |
| Hersteller Artikelnummer: | AN2168 |
| Alternativnummer: | ABT-AN2168-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Alternative Synonym: | NOG |
| Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin, and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect. |
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