Puma BH3 Domain Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Puma BH3 Domain Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP1317A-EV
• Hersteller Artikelnummer: AP1317a-ev
• Alternativnummer: ABT-AP1317A-EV-80UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IF, IHC-P, WB
• Spezies Reaktivität: Human
• Alternative Synonym: Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3, PUMA

Produktbeschreibung

PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [RB01353]
• Molekulargewicht: 20532
• NCBI: 27113
• UniProt: Q9BXH1
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target-Kategorie: This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.
• Antibody Type: Polyclonal Antibody

Bilder

Western blot analysis of anti-Puma BH3 domain