SF3B1 Antibody (N-term), Rabbit, Polyclonal

Produktübersicht

• Artikelname: SF3B1 Antibody (N-term), Rabbit, Polyclonal
• Artikelnummer: ABT-AP13754A-EV
• Hersteller Artikelnummer: AP13754a-ev
• Alternativnummer: ABT-AP13754A-EV-80UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Human, Mouse
• Alternative Synonym: Splicing factor 3B subunit 1, Pre-mRNA-splicing factor SF3b 155 kDa subunit, SF3b155, Spliceosome-associated protein 155, SAP 155, SF3B1, SAP155

Produktbeschreibung

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [RB33758]
• Molekulargewicht: 145830
• NCBI: 23451
• UniProt: O75533
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This SF3B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the N-terminal region of human SF3B1.
• Antibody Type: Polyclonal Antibody

Bilder

All lanes : Anti-SF3B1 Antibody (N-term) at 1:2000 dilutionLane 1: PANC-1 whole