CD38, Clone: [R03676], Rabbit, Polyclonal

Produktübersicht

• Artikelname: CD38, Clone: [R03676], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22413A
• Hersteller Artikelnummer: AP22413a
• Alternativnummer: ABT-AP22413A-200UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Human
• Alternative Synonym: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 3.2.2.-, 3.2.2.6, 2-phospho-ADP-ribosyl cyclase, 2-phospho-ADP-ribosyl cyclase/2-phospho-cyclic-ADP-ribose transferase, 2.4.99.20, 2-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPR hydrolase 1, T10, CD38, CD38

Produktbeschreibung

Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion (PubMed:8253715, PubMed:7961800). Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+) (PubMed:16690024). Has cADPR hydrolase activity (PubMed:8253715, PubMed:7961800).

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03676]
• Molekulargewicht: 34328
• NCBI: 952
• UniProt: P28907
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.