anti-Caspase 9 Antibody, Clone: [R03401NP], Rabbit, Polyclonal

Produktübersicht

• Artikelname: anti-Caspase 9 Antibody, Clone: [R03401NP], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22426A-EV
• Hersteller Artikelnummer: AP22426a-ev
• Alternativnummer: ABT-AP22426A-EV-50UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Alternative Synonym: Caspase-9, CASP-9, 3.4.22.62, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6

Produktbeschreibung

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage- induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03401NP]
• Molekulargewicht: 46281
• NCBI: 842
• UniProt: P55211
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This anti-Caspase 9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human anti-Caspase 9.