FOLR1 antibody, Clone: [R03821], Rabbit, Polyclonal

Produktübersicht

• Artikelname: FOLR1 antibody, Clone: [R03821], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22431A-EV
• Hersteller Artikelnummer: AP22431a-ev
• Alternativnummer: ABT-AP22431A-EV-50UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse
• Alternative Synonym: Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18, FOLR1, FOLR

Produktbeschreibung

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells (PubMed:23851396, PubMed:23934049, PubMed:2527252, PubMed:8033114, PubMed:8567728, PubMed:19074442). Has high affinity for folate and folic acid analogs at neutral pH (PubMed:23851396, PubMed:23934049, PubMed:2527252, PubMed:8033114, PubMed:8567728). Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release (PubMed:8567728). Required for normal embryonic development and normal cell proliferation (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03821]
• Molekulargewicht: 29819
• NCBI: 2348
• UniProt: P15328
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.