Catenin delta-1, Clone: [R03701], Rabbit, Polyclonal

Produktübersicht

• Artikelname: Catenin delta-1, Clone: [R03701], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22436A-EV
• Hersteller Artikelnummer: AP22436a-ev
• Alternativnummer: ABT-AP22436A-EV-50UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Alternative Synonym: Catenin delta-1, Cadherin-associated Src substrate, CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384

Produktbeschreibung

Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed:10207085, PubMed:20371349). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed:17344476).

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03701]
• Molekulargewicht: 108170
• NCBI: 1500
• UniProt: O60716
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.