CD45 antibody, Clone: [R03408], Rabbit, Polyclonal

Produktübersicht

• Artikelname: CD45 antibody, Clone: [R03408], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22447A-EV
• Hersteller Artikelnummer: AP22447a-ev
• Alternativnummer: ABT-AP22447A-EV-50UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Alternative Synonym: Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, T200, CD45, PTPRC (HGNC:9666), CD45

Produktbeschreibung

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03408]
• Molekulargewicht: 147486
• NCBI: 5788
• UniProt: P08575
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target-Kategorie: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.