p53(S315) Antibody, Clone: [R04091NP], Rabbit, Polyclonal

Produktübersicht

• Artikelname: p53(S315) Antibody, Clone: [R04091NP], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22475A-EV
• Hersteller Artikelnummer: AP22475a-ev
• Alternativnummer: ABT-AP22475A-EV-50UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse
• Alternative Synonym: Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53, P53

Produktbeschreibung

Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence (PubMed:11025664, PubMed:12524540, PubMed:12810724, PubMed:15186775, PubMed:15340061, PubMed:17317671, PubMed:17349958, PubMed:19556538, PubMed:20673990, PubMed:20959462, PubMed:22726440, PubMed:24051492, PubMed:24652652, PubMed:35618207, PubMed:36634798, PubMed:38653238, PubMed:9840937). Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type (PubMed:11025664, PubMed:12524540, PubMed:12810724, PubMed:15186775, PubMed:15340061, PubMed:17189187, PubMed:17317671, PubMed:17349958, PubMed:19556538, PubMed:20673990, PubMed:20959462, PubMed:22726440, PubMed:24051492, PubMed:24652652, PubMed:38653238, PubMed:9840937). Negatively regulates cell division by controlling expression of a set of genes required for this process (PubMed:11025664, PubMed:12524540, PubMed:12810724, PubMed:15186775, PubMed:15340061, PubMed:17317671, PubMed:17349958, PubMed:

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R04091NP]
• Molekulargewicht: 43653
• NCBI: 7157
• UniProt: P04637
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This p53(S315) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human p53(S315).