FDFT1 Antibody (Center), Rabbit, Polyclonal

Produktübersicht

• Artikelname: FDFT1 Antibody (Center), Rabbit, Polyclonal
• Artikelnummer: ABT-AP2417B
• Hersteller Artikelnummer: AP2417B
• Alternativnummer: ABT-AP2417B-400UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Human
• Alternative Synonym: Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1

Produktbeschreibung

FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [RB4781/4782]
• Molekulargewicht: 48115
• NCBI: 2222
• UniProt: P37268
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target-Kategorie: This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-170 amino acids from the Central region of human FDFT1.
• Antibody Type: Polyclonal Antibody

Bilder

Western blot analysis of FDFT1 (arr