CTDSP1 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: CTDSP1 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51124
• Hersteller Artikelnummer: AP51124
• Alternativnummer: ABT-AP51124-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1

Produktbeschreibung

Preferentially catalyzes the dephosphorylation of Ser- 5 within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 58190
• UniProt: Q9GZU7