DLX5 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: DLX5 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51165
• Hersteller Artikelnummer: AP51165
• Alternativnummer: ABT-AP51165-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, ICC, IHC-P, IP, WB
• Spezies Reaktivität: Human, Mouse
• Alternative Synonym: Homeobox protein DLX-5, DLX5

Produktbeschreibung

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5-TAATTA-3 consensus sequence for DNA-binding.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 1749
• UniProt: P56178