GRK6 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: GRK6 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51246
• Hersteller Artikelnummer: AP51246
• Alternativnummer: ABT-AP51246-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GRK6, GPRK6

Produktbeschreibung

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 2870
• UniProt: P43250