Delta Opioid Receptor Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51407
Artikelname: Delta Opioid Receptor Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51407
Hersteller Artikelnummer: AP51407
Alternativnummer: ABT-AP51407-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human, Mouse, Rat
Alternative Synonym: Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1, OPRD
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Klonalität: Polyclonal
NCBI: 4985
UniProt: P41143