PARD3 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: PARD3 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51413
• Hersteller Artikelnummer: AP51413
• Alternativnummer: ABT-AP51413-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, ICC, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: Partitioning defective 3 homolog, PAR-3, PARD-3, Atypical PKC isotype-specific-interacting protein, ASIP, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3, PAR3A

Produktbeschreibung

Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 56288
• UniProt: Q8TEW0