E3 ubiquitin-protein ligase Praja-2, Praja2, 632-, RING finger protein 131, PJA2, KIAA0438, RNF131
Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes.