SARS-CoV-2 (COVID-19) Spike P26S (Gamma Variant) Antibody [5G12G11], IgG1, Mouse, Monoclonal

Artikelnummer: ABT-ASC12213
Artikelname: SARS-CoV-2 (COVID-19) Spike P26S (Gamma Variant) Antibody [5G12G11], IgG1, Mouse, Monoclonal
Artikelnummer: ABT-ASC12213
Hersteller Artikelnummer: ASC12213
Alternativnummer: ABT-ASC12213-0.1MG
Hersteller: Abcepta
Wirt: Mouse
Kategorie: Antikörper
Applikation: ELISA, WB
Alternative Synonym: SARS-CoV-2 Spike 156-157EF antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Spike protein, Surface Glycoprotein, covid-19, sars-cov-2
In January of 2021 a new lineage of SARS-CoV-2, known as P.1 and named Gamma variant, was discovered in Japan and later spread in Brazil. It is considered a VOC (variant of concern). This variant carries 10 mutations in spike protein, including N501Y, E484K and K417T in RBD, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Gamma variant (P.1 lineage) was observed globally, which is 3.5 times more contagious as the original one. The Gamma variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent due to the immune escape E484K mutation.
Klonalität: Monoclonal
Molekulargewicht: 141178
Isotyp: IgG1
NCBI: 43740568
UniProt: P0DTC2
Puffer: SARS-CoV-2 Spike P26S (Gamma Variant) antibody is supplied in PBS containing 0.02% sodium azide.
Reinheit: Anti-SARS-CoV-2 Spike P26S (Gamma Variant) antibody is immunoaffinity chromatography purified IgG.
Target-Kategorie: It can only detect SARS-CoV-2 Gamma Variant (P.1) Spike S1 protein and does not cross-react with the spike protein of other variants.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: WB: 1 µg/mL.Antibody validated: Western Blot in human samples. Anti-SARS-CoV-2 Spike P26S (Gamma Variant) antibody specifically detects SARS-CoV-2 Gamma Variant (P.1) Spike S1 protein, but not SARS-CoV-2 WT and other variant Spike S1 protein by ELISA. All other applications and species not yet tested.