Mouse Dnmt3b Blocking Peptide (Center)

Produktübersicht

• Artikelname: Mouse Dnmt3b Blocking Peptide (Center)
• Artikelnummer: ABT-BP21512C
• Hersteller Artikelnummer: BP21512c
• Alternativnummer: ABT-BP21512C-500UG
• Hersteller: Abcepta
• Kategorie: Proteine/Peptide
• Alternative Synonym: DNA (cytosine-5)-methyltransferase 3B, Dnmt3b, DNA methyltransferase MmuIIIB, DNA MTase MmuIIIB, MMmuIIIB, Dnmt3b

Produktbeschreibung

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co- repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Function as transcriptional corepressor by associating with ZHX1 (By similarity).

Produkteigenschaften

• NCBI: 13436
• UniProt: O88509
• Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
• Target-Kategorie: The synthetic peptide sequence is selected from aa 356-370 of HUMAN Dnmt3b