FANCD2 Blocking Peptide (Center)

Produktübersicht

• Artikelname: FANCD2 Blocking Peptide (Center)
• Artikelnummer: ABT-BP21536C
• Hersteller Artikelnummer: BP21536c
• Alternativnummer: ABT-BP21536C-500UG
• Hersteller: Abcepta
• Kategorie: Proteine/Peptide
• Alternative Synonym: Fanconi anemia group D2 protein, Protein FACD2, FANCD2, FACD

Produktbeschreibung

Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.

Produkteigenschaften

• NCBI: 2177
• UniProt: Q9BXW9
• Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
• Target-Kategorie: The synthetic peptide sequence is selected from aa 893-907 of HUMAN FANCD2