GIPR Blocking Peptide (Center)

Artikelnummer: ABT-BP7495C
Artikelname: GIPR Blocking Peptide (Center)
Artikelnummer: ABT-BP7495C
Hersteller Artikelnummer: BP7495c
Alternativnummer: ABT-BP7495C-500UG
Hersteller: Abcepta
Kategorie: Proteine/Peptide
Alternative Synonym: Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR
GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
NCBI: 2696
UniProt: P48546
Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target-Kategorie: The synthetic peptide sequence is selected from aa 119-136 of HUMAN GIPR