CD3EAP is a DNA dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is a component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF activated transcription, presumably at a step following PIC formation.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target-Kategorie:
The synthetic peptide sequence used to generate the antibody AP8607a was selected from the N-term region of human CD3EAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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