TIRAP Antibody (C-term) Blocking Peptide

Produktübersicht

• Artikelname: TIRAP Antibody (C-term) Blocking Peptide
• Artikelnummer: ABT-BP8759B
• Hersteller Artikelnummer: BP8759b
• Alternativnummer: ABT-BP8759B-500UG
• Hersteller: Abcepta
• Kategorie: Proteine/Peptide
• Alternative Synonym: Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, TIRAP, MAL

Produktbeschreibung

Adapter involved in the TLR4 signaling pathway in the innate immune response. TIRAP acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, resulting in cytokine secretion and the inflammatory response.

Produkteigenschaften

• NCBI: 114609
• UniProt: P58753
• Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
• Target-Kategorie: The synthetic peptide sequence used to generate the antibody AP8759b was selected from the C-term region of human TIRAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.