C19orf61 Antibody (N-term) Blocking Peptide

Produktübersicht

• Artikelname: C19orf61 Antibody (N-term) Blocking Peptide
• Artikelnummer: ABT-BP9392A
• Hersteller Artikelnummer: BP9392a
• Alternativnummer: ABT-BP9392A-500UG
• Hersteller: Abcepta
• Kategorie: Proteine/Peptide
• Alternative Synonym: Protein SMG9, Protein smg-9 homolog, SMG9, C19orf61

Produktbeschreibung

C19orf61 is component of the SMG1C complex, a mRNA surveillance complex that recognizes and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD). In the SMG1C complex, it is required for the efficient association between SMG1 and SMG8.

Produkteigenschaften

• NCBI: 56006
• UniProt: Q9H0W8
• Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.