TNFRSF1B Antibody (C-term) Blocking Peptide

Produktübersicht

• Artikelname: TNFRSF1B Antibody (C-term) Blocking Peptide
• Artikelnummer: ABT-BP9463B
• Hersteller Artikelnummer: BP9463b
• Alternativnummer: ABT-BP9463B-500UG
• Hersteller: Abcepta
• Kategorie: Proteine/Peptide
• Alternative Synonym: Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Etanercept, Tumor necrosis factor receptor superfamily member 1b, membrane form, Tumor necrosis factor-binding protein 2, TBP-2, TBPII, TNFRSF1B, TNFBR, TNFR2

Produktbeschreibung

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Produkteigenschaften

• NCBI: 7133
• UniProt: P20333
• Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.