HFE2 Antibody (C-term) Blocking Peptide

Produktübersicht

• Artikelname: HFE2 Antibody (C-term) Blocking Peptide
• Artikelnummer: ABT-BP9699B
• Hersteller Artikelnummer: BP9699b
• Alternativnummer: ABT-BP9699B-500UG
• Hersteller: Abcepta
• Kategorie: Proteine/Peptide
• Alternative Synonym: Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC

Produktbeschreibung

HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

Produkteigenschaften

• NCBI: 148738
• UniProt: Q6ZVN8
• Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.