IST1 homolog, hIST1, Putative MAPK-activating protein PM28, IST1, KIAA0174
KIAA0174 is proposed to be involved in specific functions of the ESCRT machinery. It is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvment in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.