Batabulin (T138067) sodium is a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity, covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton, an increase in chromosomal ploidy, cell cycle arrest, and tumor cell apoptosis.
Molekulargewicht:
393.24
Reinheit:
>99%
CAS Nummer:
[195533-98-3]
Formel:
C13H6F6NNaO3S
Target-Kategorie:
Microtubule
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