Samuraciclib (ICEC0942, CT7001) is a novel oral CDK7 inhibitor with an IC50 of 40 nM. It has IC50 values for other CDK proteins such as CDK1, CDK2, CDK5 and CDK9 as 45, 15, 230 and 30 times higher than that of CDK7 IC50, respectively. ICEC0942 (CT7001) promotes cell cycle blocking and apoptosis.
Molekulargewicht:
430.98
Reinheit:
>98.5%
CAS Nummer:
[1805789-54-1]
Formel:
C22H31ClN6O
Target-Kategorie:
CDK
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