JNJ-63576253 (TRC-253) is a potent and orally active complete antagonist of the androgen receptor against F877L mutant AR and wild-type AR in LNCaP cells IC50 The values are 37 and 54 nM, respectively. JNJ-63576253 can be used in the study of castration-resistant prostate cancer (CRPC).
Molekulargewicht:
538.97
Reinheit:
>99.0%
CAS Nummer:
[2110428-64-1]
Formel:
C23H22ClF3N6O2S
Target-Kategorie:
Androgen Receptor
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