Dickkopf-related protein 1(DKK-1) secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
Reinheit:
>95%, Endotoxin<0.01 EU/ug
CAS Nummer:
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Target-Kategorie:
Cytokines and Growth Factors
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