Guggulsterone, CAS [[95975-55-6]]

Produktübersicht

• Artikelname: Guggulsterone, CAS [[95975-55-6]]
• Artikelnummer: AMO-M13379
• Hersteller Artikelnummer: M13379
• Alternativnummer: AMO-M13379-1MG,AMO-M13379-5MG,AMO-M13379-10MG,AMO-M13379-25MG,AMO-M13379-50MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: Z/E-Guggulsterone

Produktbeschreibung

Guggulsterone is a plant sterol from the gum fat of the Commiphora Wightii tree. Guggulsterone is a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC50s of 17 and 15 µM for Z- and E-Guggulsterone, respectively. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt.

Produkteigenschaften

• Molekulargewicht: 312.45
• Reinheit: >99%
• CAS Nummer: [95975-55-6]
• Formel: C21H28O2
• Target-Kategorie: Apoptosis