CC-885 is a regulator of CRBN protein with a wide range of strong CRBN-dependent anti-proliferative activity in various tumor cell lines, with enhanced anti-proliferative activity compared to lenalidomide and pomalidomide.CC-885 promotes the binding of CRBN to the novel substrate GSPT1, targeting its degradation.
Molekulargewicht:
440.88
Reinheit:
>99.0%
CAS Nummer:
[1010100-07-8]
Target-Kategorie:
Ligand for E3 Ligase
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