Inobrodib (CCS1477, CBP-IN-1) is an orally active, potent and selective p300/CBP inhibitor. inobrodib binds to p300 and CBP with Kd values of 1.3 and 1.7 nM and has a 170/130 fold selectivity compared to BRD4 with a Kd of 222 nM. Inobrodib (CCS1477) acts by inhibiting the expression and function of androgen receptor (AR) and by inhibiting c-Myc.
Molekulargewicht:
534.6
Reinheit:
>99.0%
CAS Nummer:
[2222941-37-7]
Formel:
C30H32F2N4O3
Target-Kategorie:
Epigenetic Reader Domain
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