AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC50s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC50<4.6). AH-7614 is able to block effects of both the polyunsaturated omega-6 fatty acid linoleic acid and the synthetic FFA4 agonist.
Molekulargewicht:
351.42
Reinheit:
100.0%
CAS Nummer:
[6326-06-3]
Formel:
C20H17NO3S
Target-Kategorie:
GPR/FFAR
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