SAR 256212, MM 121, Anti-Human ERBB3/ErbB 3 Recombinant Antibody
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models.
Reinheit:
>95.0%
CAS Nummer:
[1334296-12-6]
Target-Kategorie:
EGFR/HER2
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