Indusatumab vedotin (MLN-0264, AKT-264) is an antibody-drug conjugate (ADC) consisting of the human anti-guanylate cyclase C (GCC) antibody linked to a microtubule-disruptor Monomethyl auristatin . Indusatumab vedotin has anti-proliferative effects on pancreas cancer cell lines. Indusatumab vedotin arrests cell cycle at G2/M phase, and induces apoptosis.
Reinheit:
>98.0%
CAS Nummer:
[1514889-12-3]
Target-Kategorie:
Drug-Linker Conjugates for ADC
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