Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-kappa monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al.
Reinheit:
>98.5%
CAS Nummer:
[1798286-48-2]
Target-Kategorie:
PD-1/PD-L1
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