Stamulumab (MYO-029) is a recombinant human IgG1lambda antibody that binds to myostatin and neutralizes its activity by preventing binding to its endogenous high-affinity receptor ActRIIB. Stamulumab leads to muscle fiber hypertrophy and not hyperplasia in SCID mice. Stamulumab has the potential for Becker muscular dystrophy (BMD), facioscapulohumeral dystrophy (FSHD), and limb-girdle muscular dystrophy (LGMD) research.
Reinheit:
95.0%
CAS Nummer:
[705287-60-1]
Target-Kategorie:
TGF-beta/Smad
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