Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide blocks beta-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects.
Molekulargewicht:
1864.14
Reinheit:
99.0%
CAS Nummer:
[1051366-32-5]
Formel:
C84H118N24O21S2
Target-Kategorie:
CXCR
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