Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.
Molekulargewicht:
565.7
Reinheit:
99.0%
CAS Nummer:
[1187020-80-9]
Formel:
C31H36FN3O4S
Target-Kategorie:
5-HT Receptor
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